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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0444b75c7c1d900a197a01f78e9f42c5843648ace470ae9ff032d8bb4c254e16' 
  AND token = 'Whn7BmAtYLf7XY5eNFpaB98TX/mPkwDAjVaSfnF2PyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}