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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f149c1a65d7b206ac38ca5400d4f4e7c2b77d2800916cb645cb2deb78cbdc336' 
  AND token = 'u3sTARh4fhWxl8FekibjXkhXGnPs2dy0nBSgtrmDraM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}