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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dad5dbb2f34422c52016f859430eaa5b89ff0a18daad3ea84da34d84a73605c' 
  AND token = 'Uu7YEH7HTsHKgmnlCECBHmTC04BGbIdG3yZ1qhbLY4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}