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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a99badc718444a908402dfbcbc2f24caee1fd78360a3c5df2f1b9cedc9825f6d' 
  AND token = '75DjhDXKFRQCTChjeD9iaPywc/MlWy57bek1HqXuF4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}