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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba07f7b2664574de0fc4593ce3f802e4ba40466ba6e71c13e7ca19947d0b7222' 
  AND token = 'CTeW+8DCYFL8fsZLZ2tU9bYhP7GjZ/IPYLtQIVTG3b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}