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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef53c6d7a6015181702077337298e26c5d5ca5fc3f5b12d7c7986866042c9b76' 
  AND token = 'yRx5gRuv7xvXxMs2yox5A4nE7TKruR2ctHjMVbtVhfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}