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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2b3e351f5c86bd6eab8cb214377ad1dbadbe7acf0363e914c41523fee8569c' 
  AND token = 'iphOKNy3qm1tcyt4hm3QN5O0WLBDJM9dr+oHoI9WaOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}