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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c123a12b365f1ecb2e2bef83b6926445a92e038d97079f1e3186402a3c2a2da3' 
  AND token = '/lHqX6ccdGt+VXCRr9DNJKRmt90MAMi4KVYgVBs0YG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}