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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6664a26e1d254950769f08620a7878e230cacd83e76553073c67152f7a76d881' 
  AND token = 'ixTnxthS/E9DSj3BWOBYKl65IDgJOb3iRqO7kaRY9kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}