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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f1dd7133c877ef9f15078ab901e48ad206fbed80dcc5e1c22c07b0353678480' 
  AND token = 'y3OUuCj88XxcXCFl2yGBoezQLgd9Mxr0BAKrm+P1FuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}