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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82e3737a86a114c3db7c722273c60b781d1a0c3d957aedd5ec644c20ab90fe12' 
  AND token = 'PSpl1ZXhvSUYdaB/Lx3vctsxExHXaZFrBx5AdA3owRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}