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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5060eb49e7daa5d15f1ebdac687d49454324875f6ba4e597e11ed51010564907' 
  AND token = 'lG2RXouHjjBS9j1EY3xmN86Uxfr3+Sb/VVXKw4Gr+pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}