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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7a1b2350bd82d26c6be64d7452b8f4d9cc30cf888d5a742df037a008f84d3a' 
  AND token = 'A2Pr274BMAac0JW+GgCdig9uQtTDbrolJiX+0Q+MJbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}