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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '840a4d37412acd7c7a702b7c7fed6aebb667cdf1a5b7b728e0e75d9a2b39828f' 
  AND token = 'ndYYTU54TWbkICk3sEqRWzkpTcX5Z1MbghPH8AcI5qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}