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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a83059e1930f84f37a48af14c4aa646a5c18f4cf2d8e5a6c58f5a2274190baa' 
  AND token = 'ENnC406y6+lsMILSXjF9SFPiwakWP5K5XfmQgUR3UH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}