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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a03d89c5a40cc1b591f2861b04f40aee374df458af9057cfb0ef603839016a' 
  AND token = 'IEbYKd25qPDwvCImWEq+WGM21Lo7RyIt1xkrk5Nldeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}