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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68052e0588aae2885b492050ad5cfbe8ae12f0d3ea3d1d60c8893a4f2d418225' 
  AND token = 'm3z/NqR5SjFdGk0TDFVsOQpb6zlyFNqjeULUkYzK/a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}