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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f56a6e4e7866173140d740421654226c9421fc8cb839d18d2b0cab682e1d12' 
  AND token = 'pSHA4kYE2So9JD03kS5ZXLNN5dXZu9pOgNKyc+5mxFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}