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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffd2bf5023b489e35da917a6ceea481e78509d2c0c00d0d6dd0a0f301c2b0d66' 
  AND token = '870uYALQuw59zNwFSWt945pybfzvzNxdCrap9aqwcLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}