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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3682507ed67349fce58b1d8f9f7f349f61534ed5da4b7d683365373788f169' 
  AND token = '7+XCmOl2GA8caDrzMfBlT3TqnGdiW1xu/d9ilYIEaCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}