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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b309d77c2006cb85cdf9de7f4b97f0956f2dc9c03e5d81bb49c77bdeb5b9ae' 
  AND token = 'GEsOwJvmw0MPtvJWbvMrP2uRqnsNUkB+CxHmBLELTeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}