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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a93793fc03f021f9a7765d8e65c413d1f4a245f40c297bd70bdb1fcb6297d27' 
  AND token = '35PD43pCCKRikCVYQBcKOBeoYLjcTnSDaCFzPix7MO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}