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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ee57c66f1e72d0038401610347f46aed6c5d35643e2c2e73ff6869acf32dd8' 
  AND token = 'hK5J6MG7tlr0rz75AYmSYmyBel1RYvN/IsBm3ZnktRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}