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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ed28841db8892cd11874ca0ffe4b2b9140f7985896785df4abada7fe94c12c' 
  AND token = 'IZY52xpDajp4JMVkQ44rtrvK6Xq8sTwLlLINlVfdxDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}