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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6ce1af2cde5f2164560f02ffd6f0a3d8e7e50635ccb463dc2527ec853a5bfb1' 
  AND token = 'yMrwU794UPV3k+csL8WFTYZd3HDp7i2zvRJjrI0Uj/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}