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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2987c8298e5084738803fb0a1e3089a68494f3bc26dd1152762df739757e676' 
  AND token = 'VZsxGH+U7HrMa//kyxSZixa15i791RubzkpAyXu9jcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}