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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01aaaf78be1a2bec8c2016c31426a0870d185711731634e843e3d3b38f704dfc' 
  AND token = 'mbvOdsC6gvbXRyykJieXo7P1DFWoaOGPdIDQi+SjTPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}