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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ddeb6991d603ed34dfad9e2795b1f4992eecda5d8a62e88c728b8ff2410f49' 
  AND token = 'Biv+eGavTVU9jFnUf2eGA7jh+6NC0glPmA5piIRfvfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}