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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7868956f3ee3ffb7b4e389d26c67f2f0e49e18e9c3f11861938e6e1a94e67a18' 
  AND token = 'E5vDQT7Pas2AEasRvleQ7i8a2wlagXoQS1+GNWOtHUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}