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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9f0646662e447957e82e4154dcb79054ba556c6cfef493b16f20b2a07cf443a' 
  AND token = 'OUSCaps1OExa2c+H12P1r72xJHbvlMoTHHi/8SZA82k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}