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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99e5018eac1fe04a2ba8d1d6606e3402c01ca74f88ecb85ddef743ec62af07bb' 
  AND token = 'BacfjSff2NAj/HBW+2YxiLpYhnWwTpygC1S8iBLS1ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}