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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9143d3557cf6d1623f6c8bf229537520cbe5ca5582adddea4adf4c67815fa4f7' 
  AND token = 'mxaDX5nPr56oJA03wwon72nqIb7P3V3IVaVEOcxU4f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}