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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b7af3ef132235288a18b6de43f2b19805cdd6cc5bde5fdc3ef794493d90c58' 
  AND token = 'WXySGE0dAt4x5xRF0aclSgvhs6jmhb5scHY1EPB0ih8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}