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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acc7a44a5b57dcb48bd888ca07879af24bb0d50ef130888ec82199cd3acbab61' 
  AND token = 'OKxgAfbF/kR7tHW4RndUhPmxnLn6bwZKT7h59JOg4kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}