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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7e694aa62e345b49b9d02ef61d7a9c6a7a0bcb95f8a05892a68d63198efd486' 
  AND token = 'CR4j5Vx4O/AJsFxahZ6GlQIcvv2aThJ4DuNHgs9BePE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}