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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eb9d642824fc43d490e6a417ba14b4bbecf27e22e60e2471ce8a0c83854ed41' 
  AND token = 'AZcw15P4xk8aM8sWfCCBzfDKcE5IS3tyg7hcm4Wa4Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}