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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38456966aa2ed5e8b4660cf4e4788b20c1dd65cd6b1be8d22a2d34d782d3290' 
  AND token = 'lZyA1MEtRubO0Ie4XHpBB0BmSg99OYUmFPui87U/jTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}