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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3cb012e5ed133940a5ad11e0709c69b0249f5ea1a10958899da06021b5ccb80' 
  AND token = 'kxjLhZyLTvEzxHwpamyK8yyxhlDbbDjgeVDfHsYTsLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}