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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1fe5102a0b59dc847889d612367ff8b43af8f3a5230e08e589e7d7ad170ae49' 
  AND token = '6nhYmTBIn2jru82KHEk37h0Yg1ZLFxgzFRXuf6tAsNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}