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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efedcfe4a94dd1fc8c5186e89e182523e89357c6131447cbf1fbca206d3af041' 
  AND token = 'CorO937xYEF9PEqI3chdEJKd6qqijWitdt+DTZHVPyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}