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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cbd3570e49a4cec021b66cc8750ca9203b923f2170862253ced06132512e143' 
  AND token = 'PU+aNIJht59Rb+1Are4ltvBxK21TWnPmBhB4pAWT5mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}