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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c8a32e9d2e44cd695f460b9d55cb63b0100701688457d568522a06b5ef8a92' 
  AND token = '+DGIeqml/28+4UgSN/A/BMksWkt77Z/5X0e8SVAMDiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}