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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82e3e4e7fd021d905a944b9e3646679486152f04356719c4e6fed1350f73535d' 
  AND token = 'HukvxShJ3Rwy+G6qb1egxg1pTyBR721pT2Wkge+08P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}