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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fb2238d924c09faad2e92b9337fc30abd45ac32eba2a1c0cd8b00eee0a6cff' 
  AND token = 'hNCh5PFsT+OABqPJDot44VWMKPLLU8BGHHis3UvFij8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}