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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6639c2fc2bef76c00553dc4d1129be4226ff64023513baa95ccd86cce84a444' 
  AND token = 'VHg1LcfVnnpHBuE3edIBe9UAM+ID/g6sFv8hFuDNcvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}