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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4410fb0f79b614696910d97ffd1215cdbf30577680aa25bc7d7d8965e99ac5' 
  AND token = 'kGwSW54lcv+VV29OGJARk17k8tBy745OI5eoFnMMP3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}