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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817749e7db093bc8b35cef316b09d73994405fc31d45addd516e918164f4d224' 
  AND token = 'RC3zgIgfrfKvGURIitYplupfpAfpt5un68iMMRkua9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}