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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9ca8bdb672e3a8dfb0cb679ee9da8b9671fac2c7be6fac88ddaa4fa5677dac2' 
  AND token = 'Paylm00m024LOVTJjM60JTUM9239pizZxSVc9kPDbEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}