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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '868a14fdc6c60d6cc2979690980e2cc21c819b249015cee8b710c7f815180e24' 
  AND token = 'UKrURPgA7UaZ+TnxWymatdM96iNZj5V2rz7FkskdaR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}