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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e925023b1794aa6aae1317fb091dd43543b72503e0952ae5478d716984be854' 
  AND token = 'P5GQnXOJJqI69w4OxWPDEjaMU8eEcrNrYYI0xPfE8ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}